| Recent study showed that daily hormone injections could help lose weight. |
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Daily hormone injections helped dieters keep weight off in a study that helped shed light on why it is so easy to gain weight and so hard to keep it off, researchers said on Thursday.
Their study showed that the hormone leptin, useless for helping people lose weight, could help people maintain weight loss as long as they got twice-daily injections.
The finding helps researchers understand the complex way that human bodies regulate metabolism and put on fat, said Dr. Michael Rosenbaum of the Columbia University College of Physicians and Surgeons in New York.
"Anybody who has ever lost weight and tried to keep it off knows... if you manage to lose as much weight as you'd like to, it's very, very difficult to keep it off," said Rosenbaum.
In the 1990s, scientists discovered leptin, a hormone produced by fat cells that caused rats to lose weight when injected. But it failed to have the same results in humans, except for people with a defect in the leptin gene.
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